Journal: Frontiers in Cardiovascular Medicine

Article Title: Alterations of sympathetic dynamics after atrial fibrillation ablation by analysis sympathetic nerve activity provide prognostic value for recurrence and mechanistic insights into ablation

doi: 10.3389/fcvm.2022.1024156

Figure Lengend Snippet: (A) The framework for skin nerve activity (SKNA) extraction: neuECG signal was originally recorded for 10 min sampling at 10,000 Hz and the neural activity signal was extracted by a 500-Hz high-pass filter and then a 1,000 Hz low-pass filter to remove the ECG signal. (B) Illustration of the extracted iSKNA (integrated SKNA) and aSKNA (averaged SKNA) signals: (1) the recorded neuECG signal; (2) the SKNA signal after high-pass filtering; (3) the iSKNA signal was derived by rectifying and summing up the SKNA signal with a non-overlapping 100 ms time window; (4) the iSKNA signal can be further averaged for different durations (e.g., 1, 5, or 10 s) to represent the dynamics of the sympathetic system interacting with the parasympathetic system for different time frames.

Article Snippet: The electrical signal on the skin was detected using standard ECG patch electrodes connected to a fully programmable amplifier (MP36, BIOPAC, USA).

Techniques: Activity Assay, Extraction, Sampling, Derivative Assay